Direct association of pp125FAK with paxillin, the focal adhesion- targeting mechanism of pp125FAK
Focal adhesion kinase (pp125FAK) is localized to focal adhesions and tyrosine phosphorylated by the engagement of beta 1 integrins. However, it is unclear how pp125FAK is linked to integrin molecules. We demonstrate that pp125FAK is directly associated with paxillin, a 68-kD cytoskeleton protein. Th...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192281/ |