On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety
Combined treatment with trypsin, cholesterol esterase, and neuraminidase transforms LDL, but not HDL or VLDL, to particles with properties akin to those of lipid extracted from atherosclerotic lesions. Single or double enzyme modifications, or treatment with phospholipase C, or simple vortexing are...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192243/ |