Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines

Synthetic peptide analogues of sequences in the HER-2 protooncogene (HER-2) were selected based on the presence of HLA-A2.1 anchor motifs to identify the epitopes on HER-2 recognized by ovarian tumor-reactive CTL. 19 synthetic peptides were evaluated for recognition by four HLA- A2 ovarian-specific...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192068/