Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction
To study the role of the CD40-CD40 ligand interaction in the development of memory B cells and its level of action during primary antibody responses in vivo, mice were injected with a soluble CD40 fusion protein (sCD40-gamma 1), so as to block the interaction. The effects of the treatment on the pri...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1994
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191540/ |