Modulation of immunodominant sites in influenza hemagglutinin compromise antigenic variation and select receptor-binding variant viruses
The regions of antigenic variation in influenza hemagglutinin (HA) are located on surface-accessible regions in the three-dimensional structure of the HA1 monomer. The aim of this study was to establish whether a novel variant virus, IMUT4, in which we had mutated specific amino acid residues (HA1 6...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1994
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191490/ |