bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages

Neutrophils, the most common inflammatory leukocytes, have the most limited life span of all blood cells. After they undergo apoptosis, they are recognized and engulfed by macrophages. bcl-2, a proto- oncogene rearranged and deregulated in B cell lymphomas bearing the t(14;18) translocation, is know...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191411/