Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity
Mutations within the class I major histocompatibility complex (MHC) molecule that affect a peptide binding can result in strong allogeneic responses. It is believed this reflects, in part, binding of a different set of endogenous peptides by each MHC molecule. We have examined the representation of...
| Format: | Online |
|---|---|
| Language: | English |
| Published: |
The Rockefeller University Press
1994
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191347/ |