Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome
Glutamic acid decarboxylase (GAD) is the enzyme that synthesizes the neurotransmitter gamma-aminobutyric acid (GABA) in neurons and in pancreatic beta cells. It is a major target of autoimmunity in Stiff- Man syndrome (SMS), a rare neurological disease, and in insulin- dependent diabetes mellitus. T...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1993
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191306/ |