CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4
Type 1 and type 2 cloned T helper (Th) cells are believed to require different antigen-presenting cell (APC)-derived costimuli for proliferation. In the case of Th1-cloned T cells, CD28 signaling costimulates production of autocrine interleukin 2 (IL-2). Th2 cells produce their autocrine growth fact...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1993
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191256/ |