PECAM-1 is required for transendothelial migration of leukocytes

Platelet/endothelial cell adhesion molecule 1 (PECAM-1; CD31) is crucial to the process of leukocyte transmigration through intercellular junctions of vascular endothelial cells. A monoclonal antibody to PECAM, or recombinant soluble PECAM, blocks transendothelial migration of monocytes by 70-90%. P...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191108/