T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen
While recent evidence strongly suggests that the third complementarity determining regions (CDR3s) of T cell receptors (TCRs) directly contact antigenic peptides bound to major histocompatibility complex (MHC) molecules, the nature of other TCR contact(s) is less clear. Here we probe the extent to w...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1993
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191102/ |