CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help
The activation requirements for the generation of CD8+ cytotoxic T cells (CTL) are poorly understood. Here we demonstrate that in the absence of exogenous help, a CD28-B7 interaction is necessary and sufficient for generation of class I major histocompatibility complex- specific CTL. Costimulation i...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1993
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191062/ |