Histoplasma capsulatum modulates the acidification of phagolysosomes

The phagolysosome is perhaps the most effective antimicrobial site within macrophages due both to its acidity and to its variety of hydrolytic enzymes. Few species of pathogens survive and multiply in these vesicles. However, one strategy for microbial survival would be to induce a higher pH within...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191039/