Δn89β-Catenin Induces Precocious Development, Differentiation, and Neoplasia in Mammary Gland
To investigate the role of β-catenin in mammary gland development and neoplasia, we expressed a stabilized, transcriptionally active form of β-catenin lacking the NH2-terminal 89 amino acids (ΔN89β-catenin) under the control of the mouse mammary tumor virus long terminal repeat. Our results show tha...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2001
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190562/ |