Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression
The Ly and Ia phenotypes of T lymphocytes involved in different functions were characterized by the use of specific antisera. T cells responsible for delayed-type hypersensitivity (DTH) and for helper functions were found to be Ly-1+,2- in contrast to cytotoxic T cells and T cells responsible for su...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1976
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190350/ |
| Summary: | The Ly and Ia phenotypes of T lymphocytes involved in different functions were characterized by the use of specific antisera. T cells responsible for delayed-type hypersensitivity (DTH) and for helper functions were found to be Ly-1+,2- in contrast to cytotoxic T cells and T cells responsible for suppression of antibody responses which were Ly-1-,2+. Unlike some primed helper cells, T cells involved in DTH were Ia-. Suppressor cells in the system were Ia+. |
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