Separation of helper T cells from suppressor T cells expressing different Ly components. II. Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses
Cells of the Lyl subclass generate helper activity in both primary and secondary responses to sheep erythrocytes (SRBC). In contrast, after priming with SRBC, cells of the Ly-2+ subclasses, in particular Ly23 cells, have suppressive activity. The degree of Ly23-mediated suppression is directly propo...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1976
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190222/ |