Antibody response of rabbit blood lymphocytes in vitro. Kinetics, clone size, and clonotype analysis in response to streptococcal group polysaccharide antigens

Peripheral blood lymphocytes (PBL) of rabbits previously hyperimmunized against streptococcal groups A and A-variant antigens were stimulated in vitro by the corresponding vaccines to produce group-specific antibody. This response was dependent on an optimal cell density (2 X 10(6) cells/ml), on the...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1976
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190118/