Tumor-secific immunity to chemically induced tumors. Evidence for immunologic specificity and shared antigenicity in lymphocyte responses to soluble tumor antigens

Experiments were designed to explore the apparent paradox that methylcholanthrene-induced tumors of mice evoke tumor-unique transplantation immunity but reveal almost complete cross-reacting antigenicity in tests of lymphocyte behavior in vitro. The approach involved use of tumor membranes solubiliz...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1975
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189780/