Interferon γ and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of schistosoma mansoni
Macrophages play a crucial role in the defense against tumors and parasites. Activation of tumoricidal and microbicidal effector mechanisms requires stimulation of macrophages with macrophage-activating factors (MAF). One such MAF is interferon γ (IFN-γ). In some assays, substantial activity of IFN-...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1987
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189606/ |