Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells
rIL-4 inhibits the production of IFN-gamma by PBMC stimulated with mitogens or allogeneic cells. The suppression is observed at the protein and at the mRNA level; it is dose and time dependent, and it is abolished by a neutralizing mAb to IL-4. It is suggested that the balance between the production...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1989
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189501/ |