Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes

Since class I MHC glycoproteins may function by "screening and selecting" degraded proteins, we wished to determine whether very short peptides made within a cell were detected and bound by MHC, and presented for T cell perusal. We show that a 22 amino acid viral sequence containing a Db-r...

Full description

Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1989
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189441/