Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells

Graft-vs.-host (GVH)-related immunosuppression has previously been demonstrated in F1 rodent recipients of parental lymphoid cells, and has been thought to result from an immunologic attack of the donor against the host. Since all cells of such F1 recipients could potentially bear target class I MHC...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1988
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189158/