Transforming growth factor beta 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines

Transforming growth factor beta 1 (TGF-beta 1) has been shown to be associated with active centers of hematopoiesis and lymphopoiesis in the developing fetus. Therefore, the effects of TGF-beta 1 on mouse hematopoiesis were studied. TGF-beta 1 is a potent inhibitor of IL-3- induced bone marrow proli...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1988
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189000/