Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance

The ability of normal recipient-type lymphocytes to break tolerance in long-term allogenic radiation chimeras has been investigated. Reconstitution of lethally irradiated mice with a mixture of syngeneic and allogeneic T cell-depleted (TCD) bone marrow (BM) has previously been shown to lead to mixed...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1988
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188994/