Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein
Attenuated strains of Salmonella have been used effectively as vaccines against typhoid fever. We have investigated the use of such strains to deliver cloned antiphagocytic virulence determinants of unrelated bacteria. The aroA strain of S. typhimurium SL3261 was transformed with a low-copy plasmid...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1988
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188956/ |