Recombinant human macrophage colony-stimulating factor (M-CSF) requires subliminal concentrations of granulocyte/macrophage (GM)-CSF for optimal stimulation of human macrophage colony formation in vitro

Human macrophage colony-stimulating factor (M-CSF or CSF-1), either in purified or in recombinant form, is able to generate macrophagic colonies in a murine bone marrow colony assay, but only stimulates small macrophagic colonies of 40-50 cells in a human bone marrow colony assay. We report here tha...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188800/