Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma

Recombinant granulocyte/macrophage colony-stimulating factors (rGM-CSF) of mouse and human origins activated macrophages of the homologous species to inhibit the replication of the protozoan parasite T. cruzi. Activation could be induced with 10-100 ng/ml of rMu-GM-CSF, whether it was added before o...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188783/