Lipopolysaccharide modulates the expression of alpha 1 proteinase inhibitor and other serine proteinase inhibitors in human monocytes and macrophages
alpha 1 Proteinase inhibitor (PI) is the principle inhibitor of neutrophil elastase, an enzyme that degrades many components of the extracellular matrix. Expression and regulation of alpha 1 PI, therefore, affects the delicate balance of elastase and antielastase, which is critical to turnover of co...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1987
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188725/ |