Enhanced reactive lysis of paroxysmal nocturnal hemoglobinuria erythrocytes. Studies on C9 binding and incorporation into high molecular weight complexes

As part of a broader analysis of the mechanism(s) by which the most sensitive (type III) paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes are excessively sensitive to reactive lysis by isolated C5b6, C7, C8, and C9, we have compared type III PNH (PNH-III) and normal human E in respect to both...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1986
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188431/