Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy
T cell tolerance induction was examined in long-term H-2-heterozygous parent----F1 chimeras prepared with supralethal irradiation (1,300 rad). Although these chimeras appeared to be devoid of host-type APC, the donor T cells developing in the chimeras showed marked tolerance to host-type H-2 determi...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1990
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187832/ |