T cell regulation of immunoglobulin class expression in the antibody response to trinitrophenyl-ficoll. Evidence for T cell enhancement of the immunoglobulin class switch
In the absence of T cells, B cells were found to respond to the type 2 T-independent (TI-2) antigen, trinitrophenyl (TNP)-Ficoll, with a characteristic hierarchy of IgM and IgG subclass Ab production which directly correlated with 5' to 3' Igh-C gene order, i.e., IgM greater tha IgG3 great...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1982
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186620/ |