Role of Ia antigens in graft vs. host reactions. II. Molecular and functional analysis of T cell alloreactivity by the characterization of host Ia antigens on alloactivated donor T cells

Graft vs. host response (GVHR)-activated donor T cells bind to stimulatory host cell-derived Ia antigens. Radioimmune cell-binding assays demonstrate that activated donor T cells acquire both host I-A and I-E alloantigens on their surface. Approximately threefold to fivefold less I-E products than I...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1982
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186560/