The autoactivation of rabbit hageman factor

Proteolytic cleavage and activation of isolated, single chain, zymogen Hageman factor was observed in the presence of kaolin alone. The rate of cleavage of kaolin-bound Hageman factor was enhanced 50-fold by the presence of prekallikrein and high molecular weight kininogen. The two-chain 82,000 dalt...

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Bibliographic Details
Main Authors: Wiggins, RC, Cochrane, CC
Format: Online
Language:English
Published: The Rockefeller University Press 1979
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185699/