Agrin-Induced Phosphorylation of the Acetylcholine Receptor Regulates Cytoskeletal Anchoring and Clustering
At the developing neuromuscular junction, a motoneuron-derived factor called agrin signals through the muscle-specific kinase receptor to induce postsynaptic aggregation of the acetylcholine receptor (AChR). The agrin signaling pathway involves tyrosine phosphorylation of the AChR β subunit, and we...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2001
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185523/ |