Ontogeny of cell-mediated immunity. I. Early development of alloantigen- specific cytotoxic T-cell precursors in postnatal mice
Cytotoxic T-cell precursors have been shown to occur in spleens of 2-3- day-old mice. By 12 days after birth, the cytotoxic T-cell response of spleen cells to alloantigens has reached 23-32% of adult levels. Addition of extra T-helper cells did not permit cytotoxic T-cell development in spleen cells...
| Format: | Online |
|---|---|
| Language: | English |
| Published: |
The Rockefeller University Press
1977
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180800/ |