Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis in Drosophila melanogaster

Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis in Drosophila melanogaster

We describe a Drosophila gene, orbit, that encodes a conserved 165-kD microtubule-associated protein (MAP) with GTP binding motifs. Hypomorphic mutations in orbit lead to a maternal effect resulting in branched and bent mitotic spindles in the syncytial embryo. In the larval central nervous system,...

Full description

Bibliographic Details
Main Authors: Inoue, Yoshihiro H., do Carmo Avides, Maria, Shiraki, Michina, Deak, Peter, Yamaguchi, Masamitsu, Nishimoto, Yoshio, Matsukage, Akio, Glover, David M.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175100/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175100/

Similar Items