Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis

Caspases are an extended family of cysteine proteases that play critical roles in apoptosis. Animals deficient in caspases-2 or -3, which share very similar tetrapeptide cleavage specificities, exhibit very different phenotypes, suggesting that the unique features of individual caspases may account...

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Bibliographic Details
Main Authors: Mancini, Marie, Machamer, Carolyn E., Roy, Sophie, Nicholson, Donald W., Thornberry, Nancy A., Casciola-Rosen, Livia A., Rosen, Antony
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174848/