The road less traveled: transport of Legionella to the endoplasmic reticulum

Phagosomes containing the bacterial pathogen Legionella pneumophila are transported to the ER after macrophage internalization. To modulate phagosome transport, Legionella use a specialized secretion system that injects bacterial proteins into eukaryotic cells. This review will focus on recent studi...

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Main Authors: Roy, Craig R., Tilney, Lewis G.
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173838/
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spelling pubmed-21738382008-05-01 The road less traveled: transport of Legionella to the endoplasmic reticulum Roy, Craig R. Tilney, Lewis G. Mini-Reviews Phagosomes containing the bacterial pathogen Legionella pneumophila are transported to the ER after macrophage internalization. To modulate phagosome transport, Legionella use a specialized secretion system that injects bacterial proteins into eukaryotic cells. This review will focus on recent studies that have identified bacterial proteins and host processes that play a concerted role in transporting Legionella to the ER. The Rockefeller University Press 2002-08-05 /pmc/articles/PMC2173838/ /pubmed/12147677 http://dx.doi.org/10.1083/jcb.200205011 Text en Copyright © 2002, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Roy, Craig R.
Tilney, Lewis G.
spellingShingle Roy, Craig R.
Tilney, Lewis G.
The road less traveled: transport of Legionella to the endoplasmic reticulum
author_facet Roy, Craig R.
Tilney, Lewis G.
author_sort Roy, Craig R.
title The road less traveled: transport of Legionella to the endoplasmic reticulum
title_short The road less traveled: transport of Legionella to the endoplasmic reticulum
title_full The road less traveled: transport of Legionella to the endoplasmic reticulum
title_fullStr The road less traveled: transport of Legionella to the endoplasmic reticulum
title_full_unstemmed The road less traveled: transport of Legionella to the endoplasmic reticulum
title_sort road less traveled: transport of legionella to the endoplasmic reticulum
description Phagosomes containing the bacterial pathogen Legionella pneumophila are transported to the ER after macrophage internalization. To modulate phagosome transport, Legionella use a specialized secretion system that injects bacterial proteins into eukaryotic cells. This review will focus on recent studies that have identified bacterial proteins and host processes that play a concerted role in transporting Legionella to the ER.
publisher The Rockefeller University Press
publishDate 2002
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173838/
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