Trafficking of prion proteins through a caveolae-mediated endosomal pathway
To understand the posttranslational conversion of the cellular prion protein (PrPC) to its pathologic conformation, it is important to define the intracellular trafficking pathway of PrPC within the endomembrane system. We studied the localization and internalization of PrPC in CHO cells using cryoi...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2003
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173792/ |