Trafficking of prion proteins through a caveolae-mediated endosomal pathway

To understand the posttranslational conversion of the cellular prion protein (PrPC) to its pathologic conformation, it is important to define the intracellular trafficking pathway of PrPC within the endomembrane system. We studied the localization and internalization of PrPC in CHO cells using cryoi...

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Bibliographic Details
Main Authors: Peters, Peter J., Mironov, Alexander, Peretz, David, van Donselaar, Elly, Leclerc, Estelle, Erpel, Susanne, DeArmond, Stephen J., Burton, Dennis R., Williamson, R. Anthony, Vey, Martin, Prusiner, Stanley B.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173792/