Laminin γ1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve
Laminins are heterotrimeric extracellular matrix proteins that regulate cell viability and function. Laminin-2, composed of α2, β1, and γ1 chains, is a major matrix component of the peripheral nervous system (PNS). To investigate the role of laminin in the PNS, we used the Cre–loxP system to disrupt...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2003
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173689/ |