Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact
The integrin α3β1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with α3β1 via a surface loop within the α3 β-propeller (residues 242–246) but outside the laminin binding region, suggesting that uPAR–integrin interaction...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2003
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173444/ |