Brain-derived neurotrophic factor can act as a pronecrotic factor through transcriptional and translational activation of NADPH oxidase

Several lines of evidence suggest that neurotrophins (NTs) potentiate or cause neuronal injury under various pathological conditions. Since NTs enhance survival and differentiation of cultured neurons in serum or defined media containing antioxidants, we set out experiments to delineate the patterns...

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Bibliographic Details
Main Authors: Kim, Sun H., Won, Seok J., Sohn, Seonghyang, Kwon, Hyuk J., Lee, Jee Y., Park, Jong H., Gwag, Byoung J.
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173377/