CD40, an extracellular receptor for binding and uptake of Hsp70–peptide complexes
Tumor and viral antigens elicit a potent immune response by heat shock protein–dependent uptake of antigenic peptide with subsequent presentation by MHC I. Receptors on antigen-presenting cells that specifically bind and internalize a heat shock protein–peptide complex have not yet been identified....
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2002
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173242/ |