CD40, an extracellular receptor for binding and uptake of Hsp70–peptide complexes

Tumor and viral antigens elicit a potent immune response by heat shock protein–dependent uptake of antigenic peptide with subsequent presentation by MHC I. Receptors on antigen-presenting cells that specifically bind and internalize a heat shock protein–peptide complex have not yet been identified....

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Bibliographic Details
Main Authors: Becker, Thalia, Hartl, F.-Ulrich, Wieland, Felix
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173242/