Localized Ca2+ uncaging reveals polarized distribution of Ca2+-sensitive Ca2+ release sites: mechanism of unidirectional Ca2+ waves

Localized Ca2+ uncaging reveals polarized distribution of Ca2+-sensitive Ca2+ release sites: mechanism of unidirectional Ca2+ waves

Ca2+-induced Ca2+ release (CICR) plays an important role in the generation of cytosolic Ca2+ signals in many cell types. However, it is inherently difficult to distinguish experimentally between the contributions of messenger-induced Ca2+ release and CICR. We have directly tested the CICR sensitivit...

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Bibliographic Details
Main Authors: Ashby, Michael C., Craske, Madeleine, Park, Myoung Kyu, Gerasimenko, Oleg V., Burgoyne, Robert D., Petersen, Ole H., Tepikin, Alexei V.
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173122/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173122/

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