Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

In myelinated axons, K+ channels are concealed under the myelin sheath in the juxtaparanodal region, where they are associated with Caspr2, a member of the neurexin superfamily. Deletion of Caspr2 in mice by gene targeting revealed that it is required to maintain K+ channels at this location. Furthe...

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Bibliographic Details
Main Authors: Poliak, Sebastian, Salomon, Daniela, Elhanany, Hadas, Sabanay, Helena, Kiernan, Brent, Pevny, Larysa, Stewart, Colin L., Xu, Xiaorong, Chiu, Shing-Yan, Shrager, Peter, Furley, Andrew J.W., Peles, Elior
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172860/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172860/

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