The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling

The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling

Fas apoptosis inhibitory molecule (FAIM) is a protein identified as an antagonist of Fas-induced cell death. We show that FAIM overexpression fails to rescue neurons from trophic factor deprivation, but exerts a marked neurite growth–promoting action in different neuronal systems. Whereas FAIM overe...

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Bibliographic Details
Main Authors: Sole, Carme, Dolcet, Xavier, Segura, Miguel F., Gutierrez, Humberto, Diaz-Meco, Maria-Teresa, Gozzelino, Raffaella, Sanchis, Daniel, Bayascas, Jose R., Gallego, Carme, Moscat, Jorge, Davies, Alun M., Comella, Joan X.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172486/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172486/

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