DNA replication checkpoint control of Wee1 stability by vertebrate Hsl7
G2/M checkpoints prevent mitotic entry upon DNA damage or replication inhibition by targeting the Cdc2 regulators Cdc25 and Wee1. Although Wee1 protein stability is regulated by DNA-responsive checkpoints, the vertebrate pathways controlling Wee1 degradation have not been elucidated. In budding yeas...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2004
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172454/ |