SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1

SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1

The transcription factor Elk-1 is a nuclear target of mitogen-activated protein kinases and regulates immediate early gene activation by extracellular signals. We show that Elk-1 is also conjugated to SUMO on either lysines 230, 249, or 254. Mutation of all three sites is necessary to fully block SU...

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Bibliographic Details
Main Authors: Salinas, Sara, Briançon-Marjollet, Anne, Bossis, Guillaume, Lopez, Marie-Aude, Piechaczyk, Marc, Jariel-Encontre, Isabelle, Debant, Anne, Hipskind, Robert A.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172397/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172397/

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