Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells

The C-type lectin dendritic cell (DC)–specific intercellular adhesion molecule grabbing non-integrin (DC-SIGN; CD209) facilitates binding and internalization of several viruses, including HIV-1, on DCs, but the underlying mechanism for being such an efficient phagocytic pathogen-recognition receptor...

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Bibliographic Details
Main Authors: Cambi, Alessandra, de Lange, Frank, van Maarseveen, Noortje M., Nijhuis, Monique, Joosten, Ben, van Dijk, Erik M.H.P., de Bakker, Bärbel I., Fransen, Jack A.M., Bovee-Geurts, Petra H.M., van Leeuwen, Frank N., Van Hulst, Niek F., Figdor, Carl G.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171967/