Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3
14-3-3 proteins are phosphoserine/threonine-binding proteins that play important roles in many regulatory processes, including intracellular protein targeting. 14-3-3 proteins can anchor target proteins in the cytoplasm and in the nucleus or can mediate their nuclear export. So far, no role for 14-3...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171942/ |